The purported healing properties of the ripe and dried fruit vitex are derived from its whole plant extract, which contains several active constituents. This includes flavonoids (i.e. casticin, kaemperol, quercetagetin, orientin and isovitexin), iridoid glycosides (i.e. aucubin and agnoside), essential oils (i.e. limonene, cineol, pinen and sabinene), diterpenes (i.e. vitexilactone, rotundifuran and 6-β-diacetoxy-13-hydroxy-λ-8,14-dien) and essential fatty acids (oleic acid, linoleic acid, palmitic acid and stearic acid) (Dugoua, Seely, Perri, Koren & Mills, 2008).

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